P38 Kinase inhibitor 8
P38 Kinase inhibitor 8 (Compound CCLXXVIII) is an orally bioavailable small molecule that potently inhibits p38β and JNK2α2 kinases with IC50 values of 6.3 nM and 53.6 nM, respectively. It has shown efficacy in reducing inflammation in a rat collagen-induced arthritis model, supporting its use in researching inflammatory and autoimmune disease pathways.
Product Specifications
CAS Number
815595-25-6
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (N1CCC (NC=2N=CC=C (N2) C3=C (N=C4OC=CN43) C5=CC=C (F) C=C5) CC1) C
Molecular Formula
C22H21FN6O2
Molecular Weight
420.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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