MKLP2-IN-1
MKLP2-IN-1 (compound 12a) is an orally bioavailable small molecule inhibitor of the mitotic kinesin MKLP2. It potently inhibits MKLP2 ATPase activity in vitro and has demonstrated efficacy in suppressing tumor growth in a Calu-6 mouse xenograft model, supporting its use in cancer research.
Product Specifications
CAS Number
2929345-46-8
Field of Research
Signal Transduction
Smiles
O=C1N (C=2C=CC=CC2C (Br) =C (C3=NN=C (O3) C4CC4) C1) CC5=CC=C (C (F) =C5) C
Molecular Formula
C23H19BrFN3O2
Molecular Weight
468.318
Storage Conditions
-20°C
Notes
For research use only.
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