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MKLP2-IN-1

MKLP2-IN-1 (compound 12a) is an orally bioavailable small molecule inhibitor of the mitotic kinesin MKLP2. It potently inhibits MKLP2 ATPase activity in vitro and has demonstrated efficacy in suppressing tumor growth in a Calu-6 mouse xenograft model, supporting its use in cancer research.

Product Specifications

CAS Number

2929345-46-8

Field of Research

Signal Transduction

Smiles

O=C1N (C=2C=CC=CC2C (Br) =C (C3=NN=C (O3) C4CC4) C1) CC5=CC=C (C (F) =C5) C

Molecular Formula

C23H19BrFN3O2

Molecular Weight

468.318

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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