Mal-Exatecan
Mal-Exatecan (Mal-DX-8951) is a malonamide-conjugated derivative of the topoisomerase I inhibitor Exatecan, designed for constructing antibody-drug conjugates (ADCs) . It is utilized in cancer research for evaluating ADC efficacy in both in vitro cytotoxicity assays and in vivo xenograft models.
Product Specifications
CAS Number
3028213-52-4
Product Name Alternative
Mal-DX8951, Mal-DX-8951
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Purity
99.39% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (5.25 mM) ; DMSO:80 mg/mL (127.26 mM)
Smiles
N (C (CCCCCN1C (=O) C=CC1=O) =O) [C@@H]2C3=C4C (C=5N (C4) C (=O) C6=C (C5) [C@] (CC) (O) C (=O) OC6) =NC=7C3=C (CC2) C (C) =C (F) C7
Molecular Formula
C34H33FN4O7
Molecular Weight
628.65
Storage Conditions
-20°C
Notes
For research use only.
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