BRD4 degrader-5
BRD4 degrader-5 (Compound 23) is a hydrophobic-tagged molecule that induces BRD4 degradation via ER stress and autophagy, exhibiting a DC50 of 24.7 μM. It demonstrates anti-proliferative activity in 4T1 cancer cells with an IC50 of 20.6 μM, supporting its use in oncology research for studying targeted protein degradation.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery
Molecular Formula
C35H42ClN7O2S
Molecular Weight
660.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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