FGFR2/3-IN-2
FGFR2/3-IN-2 is a potent and selective oral inhibitor of FGFR2 (IC50=3.7 nM) and FGFR3 (IC50=31.2 nM) . It demonstrates antitumor efficacy, including stasis and regression, in models like SNU-16 gastric cancer, without inducing common on-target toxicities such as hyperphosphatemia or diarrhea in vivo.
Product Specifications
CAS Number
3025799-28-1
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C (N) C1=C2C=NC (=CN2C (C=3C=CC (=CC3) NC (=O) C (F) =C) =C1C4=CC=C (OC5=NC=CC (=N5) C) C=C4) C
Molecular Formula
C29H23FN6O3
Molecular Weight
522.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC228325L4V 200 µL
Gasdermin like (GSDMB) (NM_001165959) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details