KIT/PDGFRA-IN-1
KIT/PDGFRA-IN-1 (compound 19) is a dual inhibitor of wild-type and mutant KIT and PDGFRA kinases, with IC50 values ranging from sub-micromolar to high micromolar across various isoforms. Its cellular activity, demonstrated by GR50 values in GIST lines, supports its use as a research tool for investigating tyrosine kinase signaling in cancers like gastrointestinal stromal tumors.
Product Specifications
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
CC (C=CC (C (NC1=CC (C (F) (F) F) =C (NC (C=C) =O) C=C1) =O) =C2) =C2C#CC3=CN=C4N3N=CC=C4
Molecular Formula
C26H18F3N5O2
Molecular Weight
489.449
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUB2984-500 1x 500 µL
Nuclear Antigen (Pan-Nuclear Marker) (NM2984R), 0.2mg/mL
Sign In for Pricing
View Details 
