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FK 3311

FK 3311 (COX-2 Inhibitor V) is a selective inhibitor of COX-2 with antiinflammatory agent.

Product Specifications

CAS Number

[116686-15-8]

Product Name Alternative

COX-2 Inhibitor V

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/FK-3311.html

Purity

98.72

Solubility

DMSO : ≥ 100 mg/mL

Smiles

FC1=CC=C(OC2=C(NS(=O)(C)=O)C=CC(C(C)=O)=C2)C(F)=C1

Molecular Formula

C15H13F2NO4S

Molecular Weight

341.33

References & Citations

[1]Nakamura K, Ochi T, Matsuo M. [Stereoselective synthesis and pharmacological properties of metabolites of new antiinflammatory agent. 4'-Acetyl-2'- (2,4-difluorophenoxy) methanesulfonanilide (FK3311) ]. Yakugaku Zasshi. 1995 Nov;115 (11) :928-36.|[2]Sunose Y, Takeyoshi I, Tsutsumi H, Effects of FK3311 on pulmonary ischemia-reperfusion injury in a canine model. J Surg Res. 2001 Feb;95 (2) :167-73.|[3]Oshima K, Yabata Y, Yoshinari D, The effects of cyclooxygenase (COX) -2 inhibition on ischemia-reperfusion injury in liver transplantation. J Invest Surg. 2009 Jul-Aug;22 (4) :239-45.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

COX-2

Available Sizes

Curated Selection

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