FK 3311
FK 3311 (COX-2 Inhibitor V) is a selective inhibitor of COX-2 with antiinflammatory agent.
Product Specifications
CAS Number
[116686-15-8]
Product Name Alternative
COX-2 Inhibitor V
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/FK-3311.html
Purity
98.72
Solubility
DMSO : ≥ 100 mg/mL
Smiles
FC1=CC=C(OC2=C(NS(=O)(C)=O)C=CC(C(C)=O)=C2)C(F)=C1
Molecular Formula
C15H13F2NO4S
Molecular Weight
341.33
References & Citations
[1]Nakamura K, Ochi T, Matsuo M. [Stereoselective synthesis and pharmacological properties of metabolites of new antiinflammatory agent. 4'-Acetyl-2'- (2,4-difluorophenoxy) methanesulfonanilide (FK3311) ]. Yakugaku Zasshi. 1995 Nov;115 (11) :928-36.|[2]Sunose Y, Takeyoshi I, Tsutsumi H, Effects of FK3311 on pulmonary ischemia-reperfusion injury in a canine model. J Surg Res. 2001 Feb;95 (2) :167-73.|[3]Oshima K, Yabata Y, Yoshinari D, The effects of cyclooxygenase (COX) -2 inhibition on ischemia-reperfusion injury in liver transplantation. J Invest Surg. 2009 Jul-Aug;22 (4) :239-45.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
COX-2
Available Sizes
Curated Selection
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