Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

TRPV2-selective blocker 1

TRPV2-selective blocker 1 (compound IV2-1) is a selective TRPV2 channel blocker with an IC50 of 6.3 μM. TRPV2-selective blocker 1 does not affect TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 also inhibits TRPV2-mediated Ca2+ influx in macrophages, and inhibits macrophage phagocytosis[1].

Product Specifications

CAS Number

2242724-49-6

UNSPSC

12352005

Target

TRP Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/trpv2-selective-blocker-1.html

Concentration

10mM

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(CC(C)/C(C1=CC=CC=C1)=C2SCCS\2)=O

Molecular Formula

C15H18OS2

Molecular Weight

278.43

References & Citations

[1]Rick Raudszus, et al. Pharmacological inhibition of TRPV2 attenuates phagocytosis and lipopolysaccharide-induced migration of primary macrophages. Br J Pharmacol. 2023 Nov;180 (21) :2736-2749.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

TRPV2

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

N-Butyldeoxynojirimycin Hydrochloride
TRC-B691000-25MG 25 mg

N-Butyldeoxynojirimycin Hydrochloride

Sign In for Pricing
View Details
5-CR110-PEO3-amine, TFA salt
#90106 1x 5 mg

5-CR110-PEO3-amine, TFA salt

Sign In for Pricing
View Details
SH3BGR Mouse Monoclonal Antibody [Clone ID: OTI4G5]
CF812047 100 µg

SH3BGR Mouse Monoclonal Antibody [Clone ID: OTI4G5]

Sign In for Pricing
View Details
Pirin (PIR) (NM_001018109) Human Over-expression Lysate
LC422656 20 µg

Pirin (PIR) (NM_001018109) Human Over-expression Lysate

Sign In for Pricing
View Details
p53 Antibody
F49538-0.4ML 0.4 mL

p53 Antibody

Sign In for Pricing
View Details
NR0B2 (NM_021969) Human Recombinant Protein
TP760144 50 µg

NR0B2 (NM_021969) Human Recombinant Protein

Sign In for Pricing
View Details