TRPV2-selective blocker 1
TRPV2-selective blocker 1 (compound IV2-1) is a selective TRPV2 channel blocker with an IC50 of 6.3 μM. TRPV2-selective blocker 1 does not affect TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 also inhibits TRPV2-mediated Ca2+ influx in macrophages, and inhibits macrophage phagocytosis[1].
Product Specifications
CAS Number
2242724-49-6
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/trpv2-selective-blocker-1.html
Concentration
10mM
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(CC(C)/C(C1=CC=CC=C1)=C2SCCS\2)=O
Molecular Formula
C15H18OS2
Molecular Weight
278.43
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPV2
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
