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Methoxy-X04

Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques. Methoxy-X04 retains in vitro binding affinity for amyloid b (Ab) fibrils (Ki= 26.8 nM) . Methoxy-X04 is fluorescent and stains plaques, tangles, and cerebrovascular amyloid in postmortem sections of AD brain with good specificity.

Product Specifications

CAS Number

863918-78-9

Purity

>98% (HPLC)

Solubility

In Vitro: DMSO : 25 mg/mL (72.59 mM; Ultrasonic (<80°C)

Smiles

COc1cc (\C=C\c2ccc (O) cc2) ccc1\C=C\c1ccc (O) cc1

Molecular Formula

C23H20O3

Molecular Weight

344.4

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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