MTK458
MTK458 is an orally active brain penetrant PINK1 activator. MTK458 binds to PINK1 and stabilizes an active heterocomplex, thereby increasing mitophagy. MTK458 can be used for research on Parkinson's disease.
Product Specifications
CAS Number
2499962-58-0
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (300.91 mM; Ultrasonic)
Smiles
N (C1=C2C (NC (C (F) (F) F) =C2) =NC=N1) [C@H]3C=4C (CCC3) =CC=CC4
Molecular Formula
C17H15F3N4
Molecular Weight
332.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Available Sizes
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