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Nrf2-IN-3

Nrf2-IN-3 (Compound R16) is a Nrf2 inhibitor. Nrf2-IN-3 binds KEAP1 mutants (G333C mKEAP1) and repairs the disrupted KEAP1/NRF2 interactions. Nrf2-IN-3 sensitizes KEAP1-mutated cancer cells to Cisplatin (HY-17394) and Gefitinib (HY-50895) by repairing the mKEAP1/NRF2 complex.

Product Specifications

CAS Number

6325-13-9

Purity

>98% (HPLC)

Smiles

O=C (NN=CC=1C=CC=CC1O) CCCSCCCC (=O) NN=CC=2C=CC=CC2O

Molecular Formula

C22H26N4O4S

Molecular Weight

442.53

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Available Sizes

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