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AUT2

AUT2 is a Kv3.1 potassium channel modulator that shifts channel activation to more negative potentials, reducing high-threshold K+ currents. This mechanism shows promise for treating sensory hyperreactivity in Fragile X Syndrome and hearing impairments, as evidenced by its ability to restore ABR wave IV in relevant research models.

Product Specifications

CAS Number

1311137-58-2

Smiles

O=C1N (C (=O) N[C@@H]1CC) C=2C=CC (OC3=CC (C (C) C) =C (C#N) C=C3) =NC2

Molecular Formula

C20H20N4O3

Molecular Weight

364.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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