Urotensin-II receptor antagonist-1
Urotensin-II receptor antagonist-1 is a potent, selective human UT receptor antagonist (Ki=16 nM) with low oral bioavailability in rats. This research compound also exhibits off-target activity against CYP enzymes, κ opioid receptors, and cardiac sodium channels, making it a useful tool for in vitro pharmacological profiling and cardiovascular research.
Product Specifications
CAS Number
1034708-07-0
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Smiles
C ([C@H]1[C@H] (CCCN1C (CN (C) C2=CC (Cl) =C (Cl) C=C2) =O) C3=CC=CC=C3) N4CCCC4
Molecular Formula
C25H31Cl2N3O
Molecular Weight
460.439
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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