What is the catalog number for SD-436?

The catalog number for SD-436 is orb2814332.

What sizes are available for SD-436?

SD-436 is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg.

How many pack sizes does SD-436 come in?

SD-436 is available in 5 different pack sizes.

SD-436 is currently made to order / not held in immediate stock. Contact us for lead time.

SD-436

SD-436 is a potent and selective STAT3-targeting PROTAC degrader with a DC50 of 0.5 μM. It demonstrates high selectivity over other STAT family members and has been shown to induce tumor regression in mouse models of leukemia and lymphoma, supporting its use in oncology and signal transduction research.

Product Specifications

CAS Number

2497585-50-7

Product Name Alternative

SD436

Field of Research

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.34% (May vary between batches)

Smiles

C (#CCCC1CCN (C ([C@H] (CC2=CC (F) =C (F) C=C2) NC ([C@@H] (NC (=O) [C@H]3N4[C@] (CC3) (CCN (C (OC) =O) C[C@H] (NC (=O) C5=CC=6C (S5) =CC=C (C (P (=O) (O) O) (F) F) C6) C4=O) [H]) CCC (N) =O) =O) =O) CC1) C7=C8C (C (=O) N (C8) C9C (=O) NC (=O) CC9) =CC=C7