MI-1063
MI-1063 is a potent and cell-permeable MDM2 antagonist that disrupts the MDM2-p53 interaction, leading to p53 activation and tumor suppression. It demonstrates anti-proliferative activity in hematological cancer cell lines (e.g., RS4-11, MV4-11) and serves as the warhead for the PROTAC degrader MD-265 in oncology research.
Product Specifications
CAS Number
1410737-39-1
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C1[C@@]2 (C3 (N[C@@H] (C (N[C@H]4CC[C@H] (C (O) =O) CC4) =O) [C@@H]2C5=C (F) C (Cl) =CC=C5) CCCCC3) C=6C (N1) =CC (Cl) =CC6
Molecular Formula
C30H32Cl2FN3O4
Molecular Weight
588.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV810130 1.0 µg DNA
C19orf41 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details 
TA804847 100 µL
MAD2L1 binding protein (MAD2L1BP) Mouse Monoclonal Antibody [Clone ID: OTI1C11]
Sign In for Pricing
View Details K0527806 1.0 µg DNA
CTNND2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
Sign In for Pricing
View Details TL301445V 500 µL Each
SPAG16 Human shRNA Lentiviral Particle (Locus ID 79582)
Sign In for Pricing
View Details 