MI-1063
MI-1063 is a potent and cell-permeable MDM2 antagonist that disrupts the MDM2-p53 interaction, leading to p53 activation and tumor suppression. It demonstrates anti-proliferative activity in hematological cancer cell lines (e.g., RS4-11, MV4-11) and serves as the warhead for the PROTAC degrader MD-265 in oncology research.
Product Specifications
CAS Number
1410737-39-1
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C1[C@@]2 (C3 (N[C@@H] (C (N[C@H]4CC[C@H] (C (O) =O) CC4) =O) [C@@H]2C5=C (F) C (Cl) =CC=C5) CCCCC3) C=6C (N1) =CC (Cl) =CC6
Molecular Formula
C30H32Cl2FN3O4
Molecular Weight
588.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7024192-01 0.02 mg
Recombinant Salmonella typhimurium NADH-quinone oxidoreductase subunit K (nuoK)
Sign In for Pricing
View Details 
MBS7024192-02 0.1 mg
Recombinant Salmonella typhimurium NADH-quinone oxidoreductase subunit K (nuoK)
Sign In for Pricing
View Details 
MBS7024192-03 5x 0.1 mg
Recombinant Salmonella typhimurium NADH-quinone oxidoreductase subunit K (nuoK)
Sign In for Pricing
View Details 
370686-01 20 µg
Major Pollen Allergen Car b 1 isoforms 1A and 1B, Recombinant, Carpinus Betulus, aa2-160, His-Tag
Sign In for Pricing
View Details 370686-02 100 µg
Major Pollen Allergen Car b 1 isoforms 1A and 1B, Recombinant, Carpinus Betulus, aa2-160, His-Tag
Sign In for Pricing
View Details GTR15171217 1 Vial
Lentiviral mouse Nfkbil1 shRNA (UAS) - Lentiviral mouse Nfkbil1 shRNA (UAS, RFP) plasmid
Sign In for Pricing
View Details