ETD001
ETD001 is a potent and long-acting epithelial sodium channel (ENaC) inhibitor, demonstrating an IC50 of 57.5 nM in human bronchial epithelial (HBE) cells. This compound is a valuable research tool for investigating ENaC biology and its role in cystic fibrosis, supporting both in vitro and preclinical in vivo studies.
Product Specifications
CAS Number
2227484-71-9
Field of Research
Pharmacology & Drug Discovery
Smiles
C (C (O) =O) (F) (F) F.C (C ([O-]) =O) (F) (F) F.C (C) [N+]=1C=2C (N (CC) C1CNC (=O) C=3N=C4C (=NC3N) NC=C4) =CC=C (C (=O) N5CCC (N (C[C@@H] ([C@H] ([C@@H] ([C@@H] (CO) O) O) O) O) C[C@@H] ([C@H] ([C@@H] ([C@@H] (CO) O) O) O) O) CC5) C2
Molecular Formula
C41H57F6N9O16
Molecular Weight
1045.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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