WRN inhibitor 18
WRN inhibitor 18 (compound 306) is a small molecule, orally bioavailable inhibitor of the Werner syndrome helicase (WRN) . It is a research tool for investigating DNA damage response and synthetic lethality in microsatellite unstable (MSI) cancers, demonstrating antitumor efficacy in vivo models.
Product Specifications
CAS Number
3064599-42-1
Field of Research
Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology
Smiles
C (O) (=O) [C@@H]1[C@H] (C[C@H] (C[C@H]1C (NC2=C (F) C=C (C (F) (F) F) C=C2) =O) N3CCC (F) (F) C3) C4=CC=C (N (S (=O) (=O) C=5C=C6C (=CC5) N (C) C (C) =N6) C) C=C4
Molecular Formula
C35H35F6N5O5S
Molecular Weight
751.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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