FerroLOXIN-1
FerroLOXIN-1 is a selective 15LOX-2 inhibitor that potently blocks the synthesis of pro-ferroptotic HOO-ETE-PE, thereby preventing RSL3-induced ferroptosis. Its mechanism involves specific interaction with key residues like Y154. This tool compound is valuable for investigating ferroptosis pathways in both cellular and animal models of related diseases.
Product Specifications
CAS Number
2773428-48-9
Field of Research
Cell Biology, Metabolism Research
Smiles
FC1=CC=CC (=C1) N2C=C (N=C2NCC3=CC=C (C (F) =C3) C (F) (F) F) C=4C=CC=CC4
Molecular Formula
C23H16F5N3
Molecular Weight
429.39
Storage Conditions
-20°C
Notes
For research use only.
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