Lenalidomide-F
LWY713 is a potent and selective PROTAC degrader of FLT3 (DC50 = 0.64 nM) that utilizes a lenalidomide-based ligand to recruit the cereblon E3 ligase, leading to proteasomal degradation. This molecule is a valuable chemical tool for investigating FLT3 signaling and oncogenesis in both cellular and in vivo models of acute myeloid leukemia.
Product Specifications
CAS Number
2359705-88-5
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) C=3C=CC=C (F) C3C2) CC1
Molecular Formula
C13H11FN2O3
Molecular Weight
262.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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