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Lenalidomide-F

LWY713 is a potent and selective PROTAC degrader of FLT3 (DC50 = 0.64 nM) that utilizes a lenalidomide-based ligand to recruit the cereblon E3 ligase, leading to proteasomal degradation. This molecule is a valuable chemical tool for investigating FLT3 signaling and oncogenesis in both cellular and in vivo models of acute myeloid leukemia.

Product Specifications

CAS Number

2359705-88-5

Field of Research

Pharmacology & Drug Discovery

Smiles

O=C1NC (=O) C (N2C (=O) C=3C=CC=C (F) C3C2) CC1

Molecular Formula

C13H11FN2O3

Molecular Weight

262.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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