C1s-IN-1 trihydrochloride
C1s-IN-1 trihydrochloride is a selective C1s protease inhibitor (Ki=5.8 μM) that blocks classical complement pathway activation (IC50=22 μM) and also competitively inhibits thrombin (Ki=51.2 μM) . This compound is a useful research tool for studying complement-driven pathologies and coagulation cascades in vitro.
Product Specifications
CAS Number
1376162-36-5
Field of Research
Immunology & Inflammation
Smiles
N=C (C1=CN=C (N2CCN (CC2) C3=CC=CC=C3) C=C1) N.Cl.Cl.Cl
Molecular Formula
C16H22Cl3N5
Molecular Weight
390.74
Storage Conditions
-20°C
Notes
For research use only.
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