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C1s-IN-1 trihydrochloride

C1s-IN-1 trihydrochloride is a selective C1s protease inhibitor (Ki=5.8 μM) that blocks classical complement pathway activation (IC50=22 μM) and also competitively inhibits thrombin (Ki=51.2 μM) . This compound is a useful research tool for studying complement-driven pathologies and coagulation cascades in vitro.

Product Specifications

CAS Number

1376162-36-5

Field of Research

Immunology & Inflammation

Smiles

N=C (C1=CN=C (N2CCN (CC2) C3=CC=CC=C3) C=C1) N.Cl.Cl.Cl

Molecular Formula

C16H22Cl3N5

Molecular Weight

390.74

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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