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UP158

UP158 is a small molecule activator of valosin-containing protein (VCP/p97), enhancing its ATPase activity with an EC50 of 2.57 μM. This compound is a valuable research tool for studying VCP's role in cellular processes such as protein degradation and endoplasmic reticulum-associated degradation (ERAD) in both in vitro and cell-based assays.

Product Specifications

CAS Number

489402-33-7

Field of Research

Protein Biochemistry

Smiles

ClC=1C=CC=2NC=3C (=NC=NC3N4CCC5 (OCCO5) CC4) C2C1

Molecular Formula

C17H17ClN4O2

Molecular Weight

344.8

Storage Conditions

-20°C

Notes

For research use only.

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