UP158
UP158 is a small molecule activator of valosin-containing protein (VCP/p97), enhancing its ATPase activity with an EC50 of 2.57 μM. This compound is a valuable research tool for studying VCP's role in cellular processes such as protein degradation and endoplasmic reticulum-associated degradation (ERAD) in both in vitro and cell-based assays.
Product Specifications
CAS Number
489402-33-7
Field of Research
Protein Biochemistry
Smiles
ClC=1C=CC=2NC=3C (=NC=NC3N4CCC5 (OCCO5) CC4) C2C1
Molecular Formula
C17H17ClN4O2
Molecular Weight
344.8
Storage Conditions
-20°C
Notes
For research use only.
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