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FKK6

FKK6 is a selective PXR agonist (EC50 = 1.2 μM) with favorable metabolic stability and high plasma protein binding. It inhibits PXR-mediated NF-κB signaling, demonstrating anti-inflammatory effects in vitro and in a DSS-induced colitis mouse model, making it a useful research tool for studying inflammatory and metabolic diseases.

Product Specifications

CAS Number

2238839-34-2

Field of Research

Immunology & Inflammation, Signal Transduction

Smiles

O=S (=O) (C=1C=CC=CC1) N2C=3C=CC=CC3C=C2C (O) (C=4C=CN=CC4) CC#C

Molecular Formula

C23H18N2O3S

Molecular Weight

402.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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