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Fluorphine

Fluorphine is a brorphine analog and potent μ-opioid receptor (MOR) agonist, exhibiting high-affinity binding (Ki=12.5 nM) and functional activity in GTPγS (EC50=75 nM) and β-arrestin recruitment (EC50=377 nM) assays. This research chemical is used in vitro to study biased agonism and in vivo to investigate opioid-related respiratory depression.

Product Specifications

CAS Number

6440-42-2

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Smiles

O=C1NC=2C=CC=CC2N1C3CCN (CC3) C (C4=CC=C (F) C=C4) C

Molecular Formula

C20H22FN3O

Molecular Weight

339.41

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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