PF-4363467
PF-4363467 is a selective dopamine D3 receptor antagonist with high affinity (Ki=3.1 nM) and significantly lower affinity for D2R (Ki=692 nM) . It has been utilized in preclinical research to study mechanisms for reducing opioid-seeking behavior while minimizing D2-mediated side effects in both in vitro and in vivo models.
Product Specifications
CAS Number
2040055-84-1
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
CC=1C=C (C=CC1NS (=O) (=O) C2=CC=C (C (C) C) C=C2) [C@@H]3CN (CC) CCO3
Molecular Formula
C22H30N2O3S
Molecular Weight
402.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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