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PF-4363467

PF-4363467 is a selective dopamine D3 receptor antagonist with high affinity (Ki=3.1 nM) and significantly lower affinity for D2R (Ki=692 nM) . It has been utilized in preclinical research to study mechanisms for reducing opioid-seeking behavior while minimizing D2-mediated side effects in both in vitro and in vivo models.

Product Specifications

CAS Number

2040055-84-1

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

CC=1C=C (C=CC1NS (=O) (=O) C2=CC=C (C (C) C) C=C2) [C@@H]3CN (CC) CCO3

Molecular Formula

C22H30N2O3S

Molecular Weight

402.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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