EGFR-IN-138
EGFR-IN-138 (compound 19) is a potent, small-molecule EGFR inhibitor demonstrating high potency against wild-type (IC50=37 nM), L858R mutant (IC50=2.6 nM), and T790M mutant (IC50=1.9 nM) kinases. This tool compound is suitable for in vitro biochemical and cellular assays in oncology research, particularly for studying resistance mechanisms in non-small cell lung cancer models.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Molecular Formula
C42H37N7O5
Molecular Weight
719.79
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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