EGFR-IN-138

EGFR-IN-138 (compound 19) is a potent, small-molecule EGFR inhibitor demonstrating high potency against wild-type (IC50=37 nM), L858R mutant (IC50=2.6 nM), and T790M mutant (IC50=1.9 nM) kinases. This tool compound is suitable for in vitro biochemical and cellular assays in oncology research, particularly for studying resistance mechanisms in non-small cell lung cancer models.