WRN inhibitor 15
WRN inhibitor 15 (Compound 9) is a small molecule targeting the Werner syndrome helicase, exhibiting antitumor activity with IC50 values of 37.9-46.6 μM in prostate and cervical cancer cell lines. It is a useful chemical probe for in vitro studies of DNA damage response and synthetic lethality in microsatellite unstable cancers.
Product Specifications
Field of Research
Cell Biology, Epigenetics & Chromatin; Pharmacology & Drug Discovery, Molecular Biology
Molecular Formula
C16H13F2N3O
Molecular Weight
301.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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