Sesaminol
Sesaminol is an orally active Nrf2-ARE pathway activator that promotes Nrf2 nuclear translocation and upregulates antioxidant enzymes like NQO1. It demonstrates neuroprotective effects in cellular models, such as inhibiting 6-OHDA-induced ROS and apoptosis in SH-SY5Y cells, and in vivo against rotenone-induced Parkinson's pathology.
Product Specifications
CAS Number
74061-79-3
Field of Research
Immunology & Inflammation, Metabolism Research, Signal Transduction
Smiles
OC1=C ([C@@H]2[C@@]3 ([C@@] ([C@H] (OC3) C=4C=C5C (=CC4) OCO5) (CO2) [H]) [H]) C=C6C (=C1) OCO6
Molecular Formula
C20H18O7
Molecular Weight
370.35
Storage Conditions
-20°C
Notes
For research use only.
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