SPA107
SPA107 (Hemiasterlin methyl ester) is a potent antimitotic agent that inhibits tubulin polymerization with an IC50 of 0.5 nM. It demonstrates significant cytotoxicity against p53-mutated MCF-7 breast cancer cells at the same potency, making it a valuable tool for studying cytoskeleton dynamics and cancer therapeutics in vitro.
Product Specifications
CAS Number
179939-69-6
Field of Research
Signal Transduction
Smiles
C ([C@@H] (C (N[C@H] (C (N ([C@H] (/C=C (/C (OC) =O) \C) C (C) C) C) =O) [C@] (C) (C) C) =O) NC) (C) (C) C=1C=2C (N (C) C1) =CC=CC2
Molecular Formula
C31H48N4O4
Molecular Weight
540.74
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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