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IQ-1S

IQ-1S is a potent small molecule inhibitor of NF-κB and AP-1 signaling pathways, with an IC50 of 1.8 μM. It functions by binding with high affinity to JNK isoforms, particularly JNK3 (Kd 87 nM), making it a valuable tool for studying inflammation, apoptosis, and neuronal death in cellular and animal models.

Product Specifications

CAS Number

1421610-21-0

Field of Research

Signal Transduction

Smiles

[O-]N=C1C2=C (C3=CC=CC=C13) N=C4C=CC=CC4=N2.[Na+]

Molecular Formula

C15H8N3NaO

Molecular Weight

269.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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