IQ-1S

IQ-1S is a potent small molecule inhibitor of NF-κB and AP-1 signaling pathways, with an IC50 of 1.8 μM. It functions by binding with high affinity to JNK isoforms, particularly JNK3 (Kd 87 nM), making it a valuable tool for studying inflammation, apoptosis, and neuronal death in cellular and animal models.