APL-1091
APL-1091 is a maleimide-exatecan linker-MMAE conjugate designed for constructing antibody-drug conjugates (ADCs) . This cytotoxic payload-linker is utilized in ADC research for targeted delivery of the microtubule inhibitor MMAE in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
2921735-87-5
Field of Research
Metabolism Research
Smiles
[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OC (C (NCCCCCN3C (=O) C=CC3=O) =O) C4=CC=C (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CCC (O) =O) NC (C) =O) =O) CCC (O) =O) =O) C (C) C) =O) CCCNC (N) =O) =O) C=C4) =O) C) [C@@H] (C) C) =O) [C@@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C80H122N14O22
Molecular Weight
1631.91
Storage Conditions
-20°C
Notes
For research use only.
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