Lipid C2
Lipid C2 is an ionizable cationic lipid used to formulate mRNA-loaded LNPs that target the liver and spleen. In a CT26-EBV colon cancer model, LNPs with mRNA encoding EBV LMP-2, combined with anti-PD-1, reduced tumors and reversed T cell exhaustion, enhancing antigen-specific CD8+ T cell responses.
Product Specifications
CAS Number
3003022-09-8
Field of Research
Metabolism Research
Smiles
O=C (NCCN (CC (O) CCCCCCCCCCCC) CC (O) CCCCCCCCCCCC) CCN1CCN (CCC (=O) NCCN (CC (O) CCCCCCCCCCCC) CC (O) CCCCCCCCCCCC) CC1
Molecular Formula
C70H142N6O6
Molecular Weight
1163.91
Storage Conditions
-20°C
Notes
For research use only.
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