BVT-2733 hydrochloride
BVT-2733 hydrochloride is a potent, selective, and orally bioavailable non-steroidal inhibitor of 11β-HSD1, showing greater potency against the mouse enzyme (IC50=96 nM) than the human form (IC50=3341 nM) . It is a valuable research tool for studying the role of 11β-HSD1 in preclinical models of metabolic and inflammatory diseases, such as obesity and arthritis.
Product Specifications
CAS Number
376641-65-5
Field of Research
Metabolism Research
Smiles
Cl.O=C (N1CCN (C) CC1) CC=2N=C (SC2) NS (=O) (=O) C=3C=CC=C (Cl) C3C
Molecular Formula
C17H22Cl2N4O3S2
Molecular Weight
465.42
Storage Conditions
-20°C
Notes
For research use only.
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