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BVT-2733 hydrochloride

BVT-2733 hydrochloride is a potent, selective, and orally bioavailable non-steroidal inhibitor of 11β-HSD1, showing greater potency against the mouse enzyme (IC50=96 nM) than the human form (IC50=3341 nM) . It is a valuable research tool for studying the role of 11β-HSD1 in preclinical models of metabolic and inflammatory diseases, such as obesity and arthritis.

Product Specifications

CAS Number

376641-65-5

Field of Research

Metabolism Research

Smiles

Cl.O=C (N1CCN (C) CC1) CC=2N=C (SC2) NS (=O) (=O) C=3C=CC=C (Cl) C3C

Molecular Formula

C17H22Cl2N4O3S2

Molecular Weight

465.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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