Nemonoxacin

Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae, and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia[1][2][3].

Product Specifications

CAS Number

[378746-64-6]

Product Name Alternative

TG-873870

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/nemonoxacin.html

Purity

99.80

Solubility

DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CN(C2CC2)C3=C(C=CC(N4C[C@@H](N)C[C@H](C)C4)=C3OC)C1=O)O

Molecular Formula

C20H25N3O4

Molecular Weight

371.43

References & Citations

[1]Adam HJ, et al. In vitro activity of nemonoxacin, a novel nonfluorinated quinolone, against 2,440 clinical isolates. Antimicrob Agents Chemother. 2009 Nov;53 (11) :4915-20. |[2]Li CR, et al. In vivo antibacterial activity of nemonoxacin, a novel non-fluorinated quinolone. J Antimicrob Chemother. 2010 Nov;65 (11) :2411-5. |[3]Lauderdale TL, et al. Comparative in vitro activities of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, and other quinolones against clinical isolates. Antimicrob Agents Chemother. 2010 Mar;54 (3) :1338-42.