USP7-IN-16
USP7-IN-16 (Compound 61) is a potent and selective USP7 inhibitor, demonstrating single-digit nanomolar IC50 values in biochemical (FLINT) and cellular (MM.1S) assays. This compound has shown in vivo antitumor efficacy in mouse models, supporting its utility as a chemical probe for oncology research, particularly in studying ubiquitin-specific protease pathways.
Product Specifications
CAS Number
2166587-77-3
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Protein Biochemistry
Smiles
O=C1C2=C (N (C=C2) C3=CC (OC) =CC (OC) =C3) N=CN1CC4 (O) CCN (C (=O) [C@H]5[C@@H] (CN (C (=O) C=6SC (=NC6C) C=7C=CC (C) =NC7) CC5) C8=CC=CC=C8) CC4
Molecular Formula
C43H45N7O6S
Molecular Weight
787.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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