Tubulin polymerization-IN-71
Tubulin polymerization-IN-71 (Compound 4k) is a tubulin polymerization inhibitor (IC50 = 3.06 μM) with potent anti-proliferative activity against osteosarcoma cell lines MG-63 and U2OS (IC50 = 0.08-0.14 μM) . It induces G2/M phase arrest and apoptosis in MG-63 cells, making it a useful research tool for studying cytoskeleton-targeted cancer therapies.
Product Specifications
Field of Research
Cell Biology, Signal Transduction
Molecular Formula
C25H24FNO8
Molecular Weight
485.46
Storage Conditions
-20°C
Notes
For research use only.
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