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NEK7-IN-2

NEK7-IN-2 (compound 23) is a small molecule that potently disrupts the NLRP3-NEK7 interaction, stabilizing NEK7 and inhibiting NLRP3 inflammasome assembly. This action blocks IL-1β release, making it a valuable research tool for studying inflammatory diseases in both cellular and animal models of inflammation.

Product Specifications

Field of Research

Signal Transduction

Molecular Formula

C27H28F4N6O2

Molecular Weight

544.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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