SHP2-IN-34
SHP2-IN-34 (Compound A8) is a phenylurea-based allosteric inhibitor of SHP2 phosphatase. It demonstrates potent anti-tumor activity, significantly inhibiting tumor growth in CT26 mouse colon carcinoma models, supporting its use in oncology research targeting the RAS/MAPK pathway.
Product Specifications
CAS Number
2924065-12-1
Field of Research
Metabolism Research, Signal Transduction
Smiles
O=C (NC=1C=CC=C (Cl) C1) NC=2C=CC=C (SC3=NC=C (N=C3N) N4CCC (N) (C) CC4) C2Cl
Molecular Formula
C23H25Cl2N7OS
Molecular Weight
518.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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