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SHP2-IN-34

SHP2-IN-34 (Compound A8) is a phenylurea-based allosteric inhibitor of SHP2 phosphatase. It demonstrates potent anti-tumor activity, significantly inhibiting tumor growth in CT26 mouse colon carcinoma models, supporting its use in oncology research targeting the RAS/MAPK pathway.

Product Specifications

CAS Number

2924065-12-1

Field of Research

Metabolism Research, Signal Transduction

Smiles

O=C (NC=1C=CC=C (Cl) C1) NC=2C=CC=C (SC3=NC=C (N=C3N) N4CCC (N) (C) CC4) C2Cl

Molecular Formula

C23H25Cl2N7OS

Molecular Weight

518.46

Storage Conditions

-20°C

Notes

For research use only.

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