PARP1-IN-33
PARP1-IN-33 (Example 6) is a potent PARP1 inhibitor with an IC50 of 0.41 nM. It demonstrates cytoprotective effects in vitro, with an EC50 of 0.02 nM against oxidative stress in human retinal pigment epithelial cells, supporting research in retinal degeneration and cellular stress pathways.
Product Specifications
CAS Number
2640677-68-3
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
Cl.N#CC1=CC=C (C=C1) N2CCN (CC2) CCCC3=CC=4C=CC=C (F) C4C (=O) N3
Molecular Formula
C23H24ClFN4O
Molecular Weight
426.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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