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PARP1-IN-33

PARP1-IN-33 (Example 6) is a potent PARP1 inhibitor with an IC50 of 0.41 nM. It demonstrates cytoprotective effects in vitro, with an EC50 of 0.02 nM against oxidative stress in human retinal pigment epithelial cells, supporting research in retinal degeneration and cellular stress pathways.

Product Specifications

CAS Number

2640677-68-3

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Smiles

Cl.N#CC1=CC=C (C=C1) N2CCN (CC2) CCCC3=CC=4C=CC=C (F) C4C (=O) N3

Molecular Formula

C23H24ClFN4O

Molecular Weight

426.91

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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