ASM-IN-3
ASM-IN-3 (Compound 21b) is a brain-penetrant, selective acid sphingomyelinase (ASM) inhibitor with an IC50 of 3.37 μM against the human enzyme. It demonstrates in vivo efficacy by reducing depressive-like behaviors in a reserpine-induced rat model, linked to hippocampal ASM inhibition and enhanced neurogenesis, supporting its use in neuroscience research.
Product Specifications
CAS Number
2342576-75-2
Field of Research
Metabolism Research
Smiles
O=C (NO) C=1ON=C (OCC2=CC=C (C=C2) C=3C=CC (Cl) =CC3) C1
Molecular Formula
C17H13ClN2O4
Molecular Weight
344.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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