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ACP6-12

ACP6-12 is a potent small-molecule activator of the bacterial protease ClpP, exhibiting over tenfold greater activity than its predecessor ACP1-06. Its validated binding mode, confirmed by X-ray co-crystallography, makes it a valuable chemical probe for studying bacterial proteostasis and novel antibiotic mechanisms in both in vitro and cellular assays.

Product Specifications

Field of Research

Signal Transduction

Smiles

O=P (C1=NC=C (C (F) (F) F) C=C1) (C (C) (C) C (NCCSC2=C (C (F) (F) F) C=CC=C2) =O) C3=NC=C (C (F) (F) F) C=C3

Molecular Formula

C25H21F9N3O2PS

Molecular Weight

629.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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